Multisystem Inflammatory Syndrome (MIS-C), COVID-19, and Autoinflammatory Diseases in Children

As news has grown about the hyperinflammation syndrome happening in some children possibly connected with COVID-19, we know many parents of kids with periodic fever syndromes are concerned. Originally reports came out that this syndrome was similar to Kawasaki Disease, … Continue reading

Normal Body Temperature and the Periodic Fever Syndromes

For over 100 years, 98.6 degrees F (or 37 degrees C) has been accepted as the standard for a normal body temp. This became the standard after a German physician, Dr. Carl Wunderlich, recorded auxiliary (armpit) temperatures from about 25,000 … Continue reading

PFAPA vs. HIDS

Updated 2/9/2018 HIDS (hyper-IgD syndrome, a mevalonate kinase deficiency) and PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis) are both periodic fever syndromes that generally start in childhood and have very similar symptoms. It can be difficult to distinguish … Continue reading