Normal Body Temperature and the Periodic Fever Syndromes

For over 100 years, 98.6 degrees F (or 37 degrees C) has been accepted as the standard for a normal body temp. This became the standard after a German physician, Dr. Carl Wunderlich, recorded auxiliary (armpit) temperatures from about 25,000 … Continue reading

PFAPA vs. HIDS

HIDS (hyper-IgD syndrome, also known as mevalonate kinase deficiency) and PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis) are both periodic fever syndromes that generally start in childhood and have very similar symptoms. It can be difficult to distinguish … Continue reading

“It’s Just a Fever,” and Other Myths & Misconceptions About Periodic Fever Syndromes

Familial Mediterranean fever (FMF), PFAPA syndrome, cryopyrin-associated periodic syndromes (CAPS), hyperimmunoglobulinemia D with periodic fever (HIDS), or other autoinflammatory diseases probably did not make the news last night. These diseases are rare and largely unheard of except by those suffering … Continue reading