Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory bone disease. Symptoms include bone pain and bone lesions that do not have an infectious cause. Some will have recurrent fevers with flares.

Symptoms usually start in childhood, often at about 10 years old, but in some symptoms start earlier or may not start until adulthood. Many patients have symptoms for 7 to 25 years. After that bone lesions may heal completely.

This Chronic Recurrent Multifocal Osteomyelitis (CRMO) synopsis is written by expert Dr. Laxer. It covers diagnosing, treatment, and prognosis for children with CRMO.

Click here for studies on CRMO and other information that describes the symptoms, testing needed, and treatments for CRMO in more detail.

More information can also be found at the Autoinflammatory Alliance website.