What are Undifferentiated Autoinflammatory Diseases?

Updated 6/11/21 In the last 30 years, great advancements have been made in understanding how the innate immune system works and in identifying diseases that occur when there’s a malfunction in the innate immune system. In this time, the genes … Continue reading

PFAPA vs. HIDS

Updated 2/9/2018 HIDS (hyper-IgD syndrome, a mevalonate kinase deficiency) and PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis) are both periodic fever syndromes that generally start in childhood and have very similar symptoms. It can be difficult to distinguish … Continue reading

“It’s Just a Fever,” and Other Myths & Misconceptions About Periodic Fever Syndromes

Familial Mediterranean fever (FMF), PFAPA syndrome, cryopyrin-associated periodic syndromes (CAPS), hyperimmunoglobulinemia D with periodic fever (HIDS), or other autoinflammatory diseases probably did not make the news last night. These diseases are rare and largely unheard of except by those suffering … Continue reading