PFAPA vs. HIDS

Updated 2/9/2018 HIDS (hyper-IgD syndrome, a mevalonate kinase deficiency) and PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis) are both periodic fever syndromes that generally start in childhood and have very similar symptoms. It can be difficult to distinguish … Continue reading

“It’s Just a Fever,” and Other Myths & Misconceptions About Periodic Fever Syndromes

Familial Mediterranean fever (FMF), PFAPA syndrome, cryopyrin-associated periodic syndromes (CAPS), hyperimmunoglobulinemia D with periodic fever (HIDS), or other autoinflammatory diseases probably did not make the news last night. These diseases are rare and largely unheard of except by those suffering … Continue reading

My Child, or I Keep Getting Fevers. What Do I Do?

Updated 5/20/19 If you or your child keeps getting fevers, there could be several causes. These can include periodic fever syndromes, recurrent infection, immunodeficiency syndromes, mast cell activation syndrome (MCAS), or autoimmune diseases. The periodic fever syndromes, also known as … Continue reading