Normal Body Temperature and the Periodic Fever Syndromes

For over 100 years, 98.6 degrees F (or 37 degrees C) has been accepted as the standard for a normal body temp. This became the standard after a German physician, Dr. Carl Wunderlich, recorded auxiliary (armpit) temperatures from about 25,000 … Continue reading

Periodic Fever Syndromes in Adults

Updated 6/11/21 Autoinflammatory diseases, also commonly known as periodic fever syndromes, are systemic inflammatory diseases caused by malfunctions of the innate immune system. Most autoinflammatory diseases are genetic chronic lifelong diseases that typically have the first symptoms start in childhood. … Continue reading

This is Baby Olivia’s Story – The 4th Person in the World with a Newly Discovered Autoinflammatory Disease

The following was written by Jill DiStefano, Olivia’s mom. Olivia was the 4th person diagnosed with NLRC4 macrophage activation-like syndrome (NLRC4-MAS), a type of periodic fever syndrome. This is Olivia’s story and how we came to find out about her … Continue reading